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Check Carefully (1)pentobarbital will lessen the level or result of fentanyl transmucosal by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Check Closely. Coadministration of fentanyl with CYP3A4 inducers could lead to your minimize in fentanyl plasma concentrations, not enough efficacy or, probably, improvement of the with